Non-genetic Celiac Disease Test (gluten intolerance)

Celiac disease (CD), also known as gluten intolerance, is a permanent intolerance to gluten. It affects approximately 1% of the population, with a higher prevalence in women than in men.

What is gluten?

Gluten is a protein found in grains such as wheat, barley, rye, oats, spelt, kamut, and triticale. In addition to being present in food, this protein is often used as a thickening agent in many products.

What happens when someone with gluten intolerance consumes gluten?

If a person with celiac disease consumes gluten or any gluten-containing product, their immune system triggers an autoimmune response that causes inflammation and damage to the lining of the small intestine.

Celiac disease causes the body to produce antibodies that primarily attack the intestines and skin.

The small intestine has villi—tiny finger-like projections that help absorb macro- and micronutrients. When these villi are damaged by gluten consumption, nutrient absorption becomes impaired, potentially leading to a variety of symptoms and complications.

Symptoms of gluten intolerance:

• In children: Symptoms often include nausea, vomiting, diarrhea, low weight, or growth problems, among others.
• In adults: Signs are usually more subtle and may include mild diarrhea, weight loss, anemia, or in some cases, constipation.

Additionally, due to nutrient malabsorption, other symptoms may occur such as easy bruising or nosebleeds, fatigue, itchy skin (dermatitis herpetiformis), hair loss, mouth ulcers, absence of menstruation, muscle cramps, or intolerance to other nutrients like lactose.

Complications of celiac disease if not diagnosed early or if a strict gluten-free diet is not followed:

• Bone problems (osteoporosis)

• Autoimmune disorders

• Anemia

• Various types of intestinal cancer

Early diagnosis of celiac disease is crucial to prevent future complications and to help improve your quality of life.

Learn more about the non-genetic celiac disease test and how to get it with Operarme.

To diagnose celiac disease, it is recommended to measure IgA (Immunoglobulin A) anti-transglutaminase antibodies, along with total IgA levels, in case of deficiency. This is important because IgA deficiency is about 10% more common among people with celiac disease and in children under the age of 2.

In cases of IgA deficiency, IgG (Immunoglobulin G) antibody testing is used instead. While less specific, it still provides good sensitivity.

It is essential not to eliminate gluten from your diet during the diagnostic process, as doing so can interfere with the results and lead to false negatives.

The Celiac Profile: Gluten Intolerance Test is a blood test designed to detect possible celiac disease. It includes the following markers:

• Total IgA antibodies

• Anti-Gliadin IgA antibodies

• Anti-Transglutaminase IgA antibodies

If the test result is positive, you should consult your trusted doctor to better understand the severity of the intolerance and follow the most appropriate treatment plan to help restore your health and well-being.

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• First- and second-degree relatives of individuals with celiac disease.
• Patients with Type 1 Diabetes (insulin-dependent diabetes mellitus) have a higher risk of developing celiac disease than the general population. Numerous studies confirm a prevalence ranging between 2.5% and 5%.
• Individuals with autoimmune thyroid disorders (chronic autoimmune thyroiditis, Hashimoto's thyroiditis, and Graves' disease) or gastrointestinal autoimmune conditions (autoimmune hepatitis, primary biliary cirrhosis).
• Individuals with connective tissue diseases (such as rheumatoid arthritis and Sjögren’s syndrome).
• People with Down syndrome.
• Individuals with IgA deficiency.
• People with neurological disorders, including epilepsy, occipital brain calcifications, ataxia, peripheral neuropathies, dementia, multiple sclerosis, and leukoencephalopathy.

To take the Non-genetic Celiac Disease Test: Gluten Intolerance, click on the image below and follow the simple steps outlined. If you have any questions, you can contact our patient service department by calling at +34 91 141 33 56 , or fill out the contact form so we can call you back.

Once you purchase the celiac test, you will receive an email with your voucher.

After downloading the voucher for the analysis, you must call to the Laboratory's contact number and make an appointment with the Laboratory to schedule a date and time for the extraction. 

The celiac disease diagnostic test is performed by taking a blood sample, also known as serum. This test includes:

• Extraction kit
• Test to detect gluten allergy
• Results to determine gluten intolerance

To help you understand all the details of this analysis, we explain the step-by-step process, the instructions before the test, and the waiting time until you receive your results.

Step-by-Step of the celiac disease profile: Gluten Intolerance Test

The diagnosis of celiac disease is complex due to the variety of symptoms it presents. However, it is possible to detect it with simple tests, such as a serum sample and its analysis. This process, known as electrophoresis of globulins, consists of:

1. Scheduled Appointment: It is important to make an appointment with the Laboratory to schedule a date and time for the extraction. 
2. Blood sample: The blood sample is taken using a sterilized lancet. A few drops of blood from the fingertip are sufficient.
3. Sample collection: The blood sample is collected with a plastic micropipette and placed inside the detector.
4. Electrophoresis: Next, in the laboratory, the technician places the blood sample on a special paper and applies an electric current. The proteins, known as globulins in the liquid part of the blood sample, move across the paper and form bands that show the quantity of each type of protein present.
5. Analysis: After counting and analyzing the sample, the test results are obtained. An official report is then generated, which you will receive to learn about your health status—whether you have celiac disease or not.

The results of the celiac test are typically available in just 5 business days.

It is essential not to remove gluten from our diet during the diagnostic tests as it will interfere with the results and thus lead to false negatives.

It is recommended to confirm the results with your specialist, and in the case of being diagnosed with celiac disease or gluten sensitivity, a follow-up plan should be developed to eliminate symptoms and reduce the risks associated with celiac disease. 

This includes creating a diet plan tailored to you and your needs.

If you are considering taking the non-genetic celiac disease test after a recommendation from a digestive specialist, allergist, or family doctor, you can do so safely and quickly through Operarme at our partner laboratories.

You can request your Non-genetic Celiac Disease Test: Gluten Intolerance voucher immediately and easily by filling out our contact form, calling at +34 91 141 33 56 , or clicking on the following image:

¿Do you need to perform a Celiac disease test?

Make your purchase quickly and under Operarme guarantees at your nearest Megalab centre.

Purchase test