Everli Prenatal Test (Plus)

The Everli Test is a prenatal screening test that detects trisomies, abnormalities in the sex chromosomes, and major syndromes. It can be performed from the 10th week of pregnancy.

The Everli Test is one of the most comprehensive prenatal tests and is CE-IVD certified (In Vitro Diagnostic Medical Devices according to the European Directive).

With the non-invasive prenatal Everli Plus test, you can find out not only the baby’s sex but also whether the fetus presents any chromosomal, physical, or genetic abnormalities:

Trisomies

Trisomies are numerical abnormalities that occur when an individual has an extra chromosome instead of a pair. The Everli Plus Prenatal Test detects all of them:

• Patau Syndrome (Trisomy 13)
• Edwards Syndrome (Trisomy 18)
• Down Syndrome (Trisomy 21)
• Trisomies: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17, 19, 20, and 22

Sex Chromosome Aneuploidies

Sex chromosomes (X and Y) determine the fetus’s sex. The severity of these conditions varies, but most cases present only mild physical or behavioral symptoms:

• X0 (Turner Syndrome)
• XXX (Triple X Syndrome)
• XXY (Klinefelter Syndrome)
• XYY (Jacobs Syndrome)

Syndromes Detected

• DiGeorge Syndrome
• Cri-du-Chat Syndrome
• Prader-Willi Syndrome
• Angelman Syndrome
• 1p36 Deletion Syndrome
• Wolf-Hirschhorn Syndrome
• Jacobsen Syndrome
• Smith-Magenis Syndrome
• Langer-Gideon Syndrome

Is it suitable for twin pregnancies?

No, this test is not recommended for twin pregnancies. In such cases, the Everli Basic Test should be performed instead.

What is the sensitivity and specificity of the Everli Plus Test?

• Trisomies 21, 18, 13

• Sensitivity: >99.9%
• Specificity: 99.90%

• Other Aneuploidies (RAA)

• Sensitivity: 96.40%
• Specificity: 99.80%

• Deletions and duplications ≥ 7Mb

• Sensitivity: 74.10%
• Specificity: 99.80%

What happens if no results are obtained from the test?

If no results are obtained, the test will be repeated at no additional cost.

Where is the sample collected?

The blood sample is collected at Eurofins-Megalab laboratories, which operate more than 80 labs and collaborate with over 1,000 sample collection points throughout the country.

Everli Plus NIPT

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The Everli Plus Prenatal Test is a non-invasive prenatal screening recommended for pregnant women who are at high risk of aneuploidies. A high risk is considered when one or more of the following conditions are met:

• Advanced maternal age (over 30 years old)
• Ultrasound findings suggestive of aneuploidies
• Previous pregnancy with a trisomy
• Positive results from first or second trimester prenatal screening
• Presence of balanced Robertsonian translocations in the parents involving chromosomes 13 or 21

It can be performed from the 10th week of pregnancy, both in natural pregnancies and those achieved through egg donation.

The Everli Non-Invasive Prenatal Test is intended for pregnant women who are at least 10 weeks into their pregnancy, whether it's a singleton or twin pregnancy, including those achieved through egg donation.

In the case of twin pregnancies, only chromosomes 21, 18, and 13 will be analyzed. This means that sex chromosome aneuploidies will not be detected, and fetal sex will only be reported if at least one of the babies is male or if both babies are female.

The test involves analyzing fetal DNA found in the mother’s blood sample. You can expect to receive the complete results within 6 to 8 business days. Additionally, fasting is not required before undergoing the Non-Invasive Prenatal Test.

Receive your test results in just 6–8 business days.

To take the test, simply click on “Purchase Service” and follow the easy steps provided. If you have any questions, you can contact our patient support team by calling at +34 91 141 33 56 or by filling out the contact form so we can call you back.

• Once you purchase the prenatal test, you will receive a voucher via email.
• After downloading the Everli Test voucher, you can redeem it by calling the Laboratory to make an appointment.

Step-by-Step: The Everli Test

Before proceeding with the test, it’s recommended to have an ultrasound to determine the exact gestational age. This helps avoid potential anomalies that might affect the test parameters and lead to inaccurate results.

After the ultrasound, the test is performed through a single blood draw.

This is sufficient to obtain results once the sample has been analyzed. This process also helps reduce the need for further follow-up tests if a positive result is obtained.

Once the blood is drawn, the sample is sent to the laboratory for analysis, and you will then wait to receive your results.

Results

Once the sample is collected and sent for analysis, Megalab’s team of experts will prepare the results report, which will be available in less than one week.

Megalab’s team of geneticists will explain how to access your results:

• They will provide you with an access code to enter your private area.
• From there, you can check the status of your results report.
• If the results are not yet ready, it will appear as “pending.”
• Lastly, you will receive the phone number of the laboratory where you took the test, in case you have any questions while waiting for your results.

If you’re considering taking the Everli Plus test following a recommendation from gynecology experts, you can do so safely and quickly through Operarme at Megalab Laboratories.

You can request your Everli Plus Prenatal Test voucher instantly and easily by filling out our contact form, calling at +34 91 141 33 56, or by clicking on the image below:

Everli Plus NIPT

Purchase your medical voucher easily under Operarme's guarantees and select your nearest Megalab laboratory.

Purchase Test